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Cisco ISR4461 Series Integrated Services Routers: High-Performance Enterprise-Grade Wired Routers

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Network Switches
IT Hardware Experts
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The Cisco ISR4461 routers, part of Cisco’s 4000 Family of Cisco Integrated Routers, deliver an all-in-one edge-routing solution for large branch offices and medium-sized enterprises. Powered by Cisco IOS XE and a multicore x86 architecture, these enterprise-grade routers support up to 1.5 Gbps default throughput (upgradeable to 3 Gbps via license) and over 7 Gbps of CEF-only routing performance.

With integrated SD-WAN, on-box security, modular expansion slots, and zero-touch provisioning, the ISR4461 series provides secure, scalable, and flexible wired routing for today’s digital enterprises.

Product Overview

Specification

Feature Cisco ISR4461/K9
Default Throughput 1.5 Gbps
Performance License Throughput 3 Gbps
CEF-Only (Boost License) Throughput > 7 Gbps
Onboard GE Ports 4 (10/100/1000 RJ-45)
Onboard SFP Ports 4 (1 Gbps SFP)
NIM Slots 3 (Network Interface Module slots)
Enhanced SM-X Slots 3 (Service Module slots)
ISC Slot 1 (Integrated Services Card)
DRAM (Default) Data-Plane: 2 GB; Control/Services: 4 GB
DRAM (Maximum) Data-Plane: 2 GB; Control/Services: 16 GB
Flash Memory (Default/Max) 8 GB / 32 GB
CPU Architecture Multicore x86
Embedded Security & SD-WAN Cisco SD-WAN, IPsec, optional NGFW/IPS/AMP/URLF
Power Supplies Dual 650 W DC reverse-air (optional AC)
Form Factor 1 RU rack-mountable

Core Features

  1. Multicore x86 Architecture
    Separates control, data, and services planes to ensure consistent routing performance even when running SD-WAN, firewall, and advanced services concurrently .
  2. High Throughput & Flexible Licensing
    Base model delivers 1.5 Gbps of encrypted IPsec VPN; licenses boost to 3 Gbps, and CEF-only boost unlocks over 7 Gbps of pure routing performance.
  3. Integrated SD-WAN & On-Box Security
    Policy-driven overlay tunnels across MPLS, broadband, and LTE; optional NGFW, Snort IPS, Advanced Malware Protection, and URL Filtering protect branch traffic.
  4. Modular Expansion
    Three NIM slots for WAN interfaces (LTE, T1/E1, PoE), three SM-X slots for services modules, and one ISC slot for additional compute or storage module.
  5. Trustworthy Solutions
    Secure Boot, hardware root of trust, and Secure Unique Device Identifier (SUDI) safeguard firmware and configuration integrity from factory to runtime.
  6. Zero-Touch Provisioning & Automation
    Cisco Plug and Play (PnP) combined with DNA Center integration enables automated onboarding, configuration, and lifecycle management, cutting deployment time by up to 70% .
  7. Scalable SD-WAN Overlay Tunnels
    Supports up to 2,500 simultaneous tunnels for secure, application-aware connectivity across distributed sites.
  8. Comprehensive Memory & Storage
    Separate DRAM planes and up to 32 GB flash support large configurations, logs, and on-box virtual network functions.

Competitor Comparison

Feature Cisco ISR4461 FortiGate 200E Juniper SRX1500
Default Throughput 1.5 Gbps 1 Gbps 1.5 Gbps
Performance License 3 Gbps 3.5 Gbps 3 Gbps
CEF-Only Throughput > 7 Gbps 10 Gbps 6 Gbps
Embedded Security NGFW, IPS, AMP, URLF (on-box) NGFW, IPS, SSL Inspection NGFW, IPS
Modularity 3 NIM, 3 SM-X, 1 ISC Fixed appliance 2 service cards
SD-WAN Support Cisco Catalyst SD-WAN FortiOS Secure SD-WAN Juniper Secure Connect

Installation and Setup

Technical Guides

Site Survey & Rack Planning

Evaluate rack space, power options (AC/DC), and airflow. Plan module usage (NIM, SM-X, ISC) before installation.

License Activation

license install flash:perf-license.pkg

reload

SD-WAN Overlay Configuration

sdwan

overlay name branch-overlay

exit

interface GigabitEthernet0/2

sdwan transport interface color biz-internet

no shutdown

Security Policy Deployment

security

ip inspect name NGFW protocol tcp

url-filtering enable

malware-defense enable

Module Installation with OIR

hw-module subslot 0 power off

install module NIM-4G-LTE

hw-module subslot 0 power on

Memory & Flash Upgrades

show platform hardware memory status

show flash:

Rolling Software Upgrades

request platform software package install switch

CLI Configuration Examples

Enable SD-WAN

configure terminal

sdwan

Define Overlay and VPN Profile

configure terminal

crypto ikev2 proposal ipsec-prop

encryption aes-gcm

integrity sha256

exit

crypto ipsec profile ipsec-br

set ikev2 ipsec-prop ipsec-prop

Configure WAN Interface for SD-WAN

configure terminal

interface GigabitEthernet0/2

description Internet-Link

sdwan transport interface color biz-internet

no shutdown

Create Tunnel Interface

configure terminal

interface Tunnel0

ip address 10.1.1.1 255.255.255.252

tunnel source GigabitEthernet0/2

tunnel mode ipsec ipv4

tunnel protection ipsec profile ipsec-br

Activate Next-Gen Firewall

configure terminal

license boot module isr4461 sec

security

Real Case Studies and Scenarios

1. Global Retail Chain
A leading retailer rolled out ISR4461 at 250 locations. Zero-touch provisioning via DNA Center reduced site activation from days to hours, while SD-WAN across MPLS and broadband increased application uptime to 99.99%.

2. Healthcare Network Modernization
A regional hospital deployed ISR4461 with on-box NGFW and AMP for HIPAA-compliant telemedicine. The solution delivered 1.5 Gbps of secure throughput, supporting real-time imaging and patient monitoring across multiple campuses.

3. Financial Services Branches
A financial institution replaced legacy routers with ISR4461 to host containerized compliance and analytics functions. The multicore design offloaded services to the control plane, improving transaction processing latency by 35% under peak loads.

Frequently Asked Questions (FAQs)

  1. What is the default and boosted throughput of the ISR4461?
    The router delivers 1.5 Gbps by default and can be upgraded to 3 Gbps with a license; a boost license unlocks over 7 Gbps of routing performance.
  2. How many ports does the ISR4461 have?
    It provides 4× RJ-45 GE ports and 4× 1 Gbps SFP ports for flexible WAN/LAN configurations.
  3. What expansion slots are available?
    Three NIM slots, three Enhanced SM-X slots, and one ISC slot support WAN modules, services modules, and virtual network functions.
  4. Can ISR4461 host security services on-box?
    Yes—NGFW, Snort IPS, Cisco AMP, and URL Filtering can run locally via the Security bundle.
  5. Does the router support SD-WAN?
    Fully integrated Cisco Catalyst SD-WAN with zero-touch provisioning and policy-based overlays is supported.
  6. How much memory and storage can I install?
    Default 2 GB data-plane and 4 GB control-plane DRAM, expandable to 16 GB; flash from 8 GB to 32 GB.
  7. What power options are available?
    Supports dual 650 W DC reverse-air power supplies; optional AC power via rack-mount accessory.

Conclusion

The Cisco ISR4461 Integrated Services Routers combine high-performance wired routing, SD-WAN, and advanced on-box security in a modular, enterprise-grade router platform.

With flexible licensing, multicore architecture, and extensive expansion slots, the ISR4461 scales to meet the evolving connectivity and security needs of branch offices.

Integrated with Cisco DNA Center for zero-touch provisioning and automated management, this Cisco router simplifies operations while delivering secure, resilient, and future-proof WAN services.

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