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Cisco ISR4451 Series Integrated Services Routers: High-Performance Enterprise-Grade Wired Routers

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Network Switches
IT Hardware Experts
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The Cisco ISR4451 routers are part of the Cisco 4000 Family of Cisco integrated routers, delivering a robust, all-in-one edge platform for branch offices and small-to-midsize enterprises.

Built on Cisco IOS XE software and a multicore x86 architecture, the ISR4451 supports up to 1 Gbps of default encrypted throughput and can be upgraded to 2 Gbps with a performance license, making it an ideal choice for demanding WAN environments.

With on-box SD-WAN, advanced security services, and flexible modularity, these enterprise-grade routers enable secure, high-performance connectivity and application convergence in a compact 1 RU form factor.

Product Overview

Specification

Feature Cisco ISR4451-X/K9
Default Aggregate Throughput 1 Gbps
Performance License Throughput 2 Gbps
CEF-Only (Boost License) Throughput > 4 Gbps
Onboard 10/100/1000 Ports (RJ-45) 4
Onboard 1 Gbps SFP Ports 4
Enhanced SM-X Service-Module Slots 2
Doublewide SM-X Slots 1 (when no singlewide SM-X installed)
NIM Slots 3
Onboard ISC Slot 1
DRAM (Default) Data-Plane: 2 GB; Control/Services: 4 GB
DRAM (Maximum) Data-Plane: 2 GB; Control/Services: 16 GB
Flash Memory (Default/Max) 8 GB / 32 GB
CPU Architecture Multicore x86
Embedded Security & SD-WAN SD-WAN, IPsec, optional NGFW/IPS/AMP, URLF
Form Factor 1 RU rack-mount

Core Features

  1. Multicore x86 Architecture
    The ISR4451’s multicore processor separates control, data, and services planes. This ensures consistent routing performance even when running multiple on-box services, such as Cisco Catalyst SD-WAN and advanced security features, concurrently.
  2. High Throughput with Flexible Licensing
    Out of the box, the router delivers up to 1 Gbps of IPsec VPN throughput. A simple license upgrade doubles this to 2 Gbps, and an optional boost license unlocks over 4 Gbps of CEF-only throughput for raw routing performance.
  3. Integrated SD-WAN and Advanced Security
    Cisco Catalyst SD-WAN services offer policy-driven overlay tunnels and intelligent path selection across MPLS, broadband, and LTE links. Optional on-box security bundles provide NGFW, Snort IPS, Cisco AMP, and URL Filtering for unified threat defense.
  4. Modular Expansion Slots
    Three NIM slots, two Enhanced SM-X slots, and one Integrated Services Card (ISC) slot accommodate WAN interface modules, voice DSP modules (PVDM4), storage expansions, and containerized applications, all with Online Insertion and Removal (OIR) support.
  5. Comprehensive Memory and Storage
    Separate control/services and data-plane DRAM planes (4 GB and 2 GB default) can be upgraded independently for optimized performance. Flash memory can be expanded from 8 GB to 32 GB to support large configurations, logs, and on-box VNFs.
  6. Trustworthy Solutions
    Secure Boot, hardware Root of Trust, and Secure Unique Device Identification (SUDI) ensure platform integrity from factory to runtime, mitigating supply-chain and runtime threats.
  7. Zero-Touch Provisioning & Automation
    Integration with Cisco DNA Center and Plug-and-Play capability enables automated onboarding, configuration, and lifecycle management, reducing branch deployment time by up to 70%.
  8. Scalable SD-WAN Overlay Tunnels
    Supports up to 2,500 SD-WAN tunnels for secure, application-aware connectivity, allowing consolidation of multiple branch sites and optimized traffic steering.

Competitor Comparison

Capability Cisco ISR4451 FortiGate 200E Juniper SRX 1500
IPsec VPN Throughput 2 Gbps (perf. license); > 4 Gbps CEF 10 Gbps 7 Gbps
SD-WAN Support Cisco Catalyst SD-WAN FortiOS Secure SD-WAN Juniper Secure Connect
Embedded Security NGFW, IPS, AMP, URLF (on-box) NGFW, IPS, Antivirus, SD-WAN NGFW, IPS, UTM
Modular Expansion 3 NIM, 2 SM-X, 1 ISC slot Fixed appliance 2 service cards
Management Platforms Cisco DNA Center, CLI, SNMP FortiManager, FortiCloud Juniper Mist, CLI
Form Factor 1 RU rack-mount Desktop/1 RU optional rack 1 RU rack

Installation and Setup

Technical Guides

Site Survey & Rack Planning

  • Assess available rack space and power (AC/DC), and plan for module slot usage (NIM, SM-X, ISC).
  • Ensure adequate airflow and cable management for optimal thermal performance.

License Activation

  • Use license install flash:performance.lic to enable higher throughput.
  • Enable security services with license boot module isr4451 sec; reload to activate NGFW/IPS/AMP.

SD-WAN Overlay Configuration

sdwan

overlay name branch-overlay

exit

interface GigabitEthernet0/2

sdwan transport interface color biz-internet

no shutdown

Security Policy Deployment

security

ip inspect name NGFW policy

inspect ngfw

url-filtering enable

malware-defense enable

exit

Module Installation (OIR)

hw-module subslot 0 power off

install module SM-X-4G-LTE

hw-module subslot 0 power on

Memory Upgrade

  • Insert matched 8 GB DDR3 ECC DIMMs in pairs for control plane memory expansion to 16 GB.
  • Verify with show platform hardware memory status.

Firmware Maintenance

Schedule rolling IOS XE updates via Cisco DNA Center or:  

request platform software package install profile dna

CLI Configuration Examples

Enable and Enter SD-WAN Configuration

configure terminal

sdwan

Create SD-WAN Overlay

configure terminal

sdwan

overlay name branch-overlay

Configure WAN Interfaces

configure terminal

interface GigabitEthernet0/2

description Internet-Link

sdwan transport interface color biz-internet

no shutdown

Apply IPsec Profile to Tunnel

configure terminal

crypto ikev2 proposal ipsec-prop

encryption aes-gcm

integrity sha256

exit

crypto ipsec profile ipsec-profile

set ikev2 ipsec-prop ipsec-prop

exit

interface Tunnel0

ip address 10.1.1.1 255.255.255.252

tunnel source GigabitEthernet0/2

tunnel mode ipsec ipv4

tunnel protection ipsec profile ipsec-profile

Activate Next-Gen Firewall

configure terminal

license boot module isr4451 sec

security

Real Case Studies and Scenarios

  1. Global Retail Chain
    A multinational retailer deployed ISR4451-X in 300 stores. Zero-touch provisioning via Cisco DNA Center reduced rollout time by 60%, and SD-WAN multiplexed broadband and LTE links for sub-second failover, ensuring uninterrupted point-of-sale services.
  2. Healthcare Campus WAN Consolidation
    A major hospital integrated ISR4451-X with on-box NGFW and Cisco Umbrella SIG for HIPAA-compliant security. With 2 Gbps aggregate throughput, they supported real-time telemedicine, electronic health records access, and medical IoT devices without latency.
  3. Financial Services Branch Network
    A regional bank replaced legacy routers with ISR4451-X to run containerized compliance and analytics apps. The multicore architecture offloaded services to the programmable plane, improving transaction processing times by 40% during peak hours.

Frequently Asked Questions (FAQs)

  1. What is the default and maximum throughput of the Cisco ISR4451?
    The router delivers 1 Gbps by default and can be upgraded to 2 Gbps with a performance license; an optional boost license unlocks > 4 Gbps of raw routing throughput.
  2. How many WAN/LAN ports are onboard?
    It includes 4× 10/100/1000 RJ-45 ports and 4× 1 Gbps SFP ports for flexible WAN or LAN connectivity.
  3. What expansion slots does the ISR4451 offer?
    Three NIM slots, two Enhanced SM-X slots, and one Integrated Services Card (ISC) slot support expandable interfaces and services.
  4. Which security services can I run on-box?
    Optional container-based NGFW, Snort IPS, Cisco AMP, and URL Filtering are available via the Security bundle.
  5. Does the router support SD-WAN?
    Yes—Cisco Catalyst SD-WAN is fully integrated, enabling policy-driven overlay tunnels and zero-touch provisioning.
  6. How much memory and storage can be installed?
    Default 2 GB data-plane and 4 GB control-plane DRAM can be upgraded (control-plane to 16 GB). Flash can be expanded from 8 GB to 32 GB.
  7. What management options are available?
    Manage via Cisco DNA Center, CLI, SNMP, REST APIs, or Embedded Event Manager for comprehensive automation and analytics.

Conclusion

The Cisco ISR4451 integrated routers deliver a premium enterprise-grade router platform, combining high-performance routing, SD-WAN, and advanced security in a modular, compact package.

With pay-as-you-grow licensing, multicore performance, and extensive expansion slots, the ISR4451 scales to meet evolving branch office requirements.

Integrated with Cisco DNA Center for zero-touch deployment and automated lifecycle management, this wired router simplifies operations while ensuring robust, secure connectivity for today’s digital-first enterprises.

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